Cancer-resistant mice
Beutler, Bruce (United States of America)
16:00h - 17:00h
Transcription of the genome: from molecular mechanism to cellular regulation
Cramer, Patrick (Germany)
18:30h - 19:30h
Symposia
Silver Room
30.6.2024
08:30 – 10:30h
Methods and progress in structural biology – part A
Chairs: Martino Bolognesi (IT) Eleonore von Castelmur (SW)
Deciphering the molecular structure of muscle Z-disk assembly: an integrative structural biology approach
Djinovic Carugo, Kristina (Austria)
08:30h - 09:00h
Symposia
Silver Room
30.6.2024
08:30 – 10:30h
Methods and progress in structural biology – part A
Chairs: Martino Bolognesi (IT) Eleonore von Castelmur (SW)
Beyond Structures: Deciphering the Regulatory Interplay between Cell-Wall Degrading Machineries and Bacterial Cell Division
Hermoso, Juan A. (Spain)
08:30h - 09:00h
Symposia
Red Room
30.6.2024
08:30 – 10:30h
Cutting edge approaches for sustainable and environmental technology
Chairs: Chiara Schiraldi (IT) Uwe Bornscheuer (DE)
Biotechnological processing of seaweed for value added products
Nordberg Karlsson, Eva (Sweden)
09:00h - 09:30h
Symposia
Blue Room
30.6.2024
08:30 – 10:30h
Biochemistry of physical activity and health – part A
Chairs: Viberto Stocchi (IT) Paul Greenhaff (UK)
Exercise as medicine in a translational perspective: focus on myokines
Pedersen, Bente Klarlund (Denmark)
08:30h - 09:00h
Deciphering DNA-protein crosslink repair in vivo using CRISPR/Cas genome editing in a zebrafish model
Popovic, Marta (Croatia)
09:00h - 09:30h
Innate immunity and inflammation: from molecules to cancer and COVID-19
Mantovani, Alberto (Italy)
11:00h - 12:00h
The century of vision in protein biochemistry
Huber, Robert (Germany)
12:00h - 12:45h
Loss of heterochromatin drives increased genome instability in aging and cancer
GASSER, Susan M (Switzerland)
16:00h - 16:30h
Plenary Lectures
Silver Room
30.6.2024
15:30 – 16:00h
The FEBS Journal Lecture
Clathrin-mediated membrane traffic and mechanisms of tissue specialization
Brodsky, Frances (United Kingdom)
15:30h - 16:00h
Translational proteomics of rare diseases and the journey towards precision medicine
GUERRERA, Chiara (France)
17:00h - 17:30h
Symposia
Blue Room
30.6.2024
17:00 – 19:00h
Bio-based polymers for engineered green materials
Chairs: Loredana Mariniello (IT) Jan Willem Borst (NL)
Tuning the properties of biopolymers: from biowaste towards more sustainable advanced materials
de la Caba, Koro (Spain)
17:00h - 17:30h
Special Sessions
Yellow Room 2+3
30.6.2024
17:00 – 19:00h
Science & Society: Private and public funds in translational research
Chairs: Mauro Magnani (IT) Emmanouil Fragkoulis (GR)
CDP Venture Capital’s Technology Transfer model
Claudia Pingue (Italy)
17:00h - 17:30h
Special Sessions
Yellow Room 2+3
30.6.2024
17:00 – 19:00h
Science & Society: Private and public funds in translational research
Chairs: Mauro Magnani (IT) Emmanouil Fragkoulis (GR)
Maintaining a long breath: building a long-term vision to advance translational research
Ellmeier, Wilfried (Austria)
17:00h - 17:30h
Highly multiplexed quantitative Epigenome Profiling for Drug Screening and Biomarker Discovery
Elsässer, Simon (Sweden)
17:30h - 18:00h
Mitochondrial signaling - touch me, don't touch me, just be sweet
Raimundo, Nuno (United States of America)
08:30h - 09:00h
Chasing spectral shadows into the dark proteome. How cultural heritage is making us question our assumptions about the analysis of old proteins
Collins, Matthew (Denmark)
08:30h - 09:00h
Decoding Biomolecules and their Networks in Artists’ Materials using Layer-by-Layer High Resolution MALDI Imaging and CrossLinking Mass Spectrometry
TOKARSKI, Caroline (France)
08:30h - 09:00h
Impact of dietary polyphenols on brain functions through the gut-brain axis modulation
Vauzour, David (United Kingdom)
08:30h - 09:00h
Microplastics and proteins interplay in food and environment
Cirkovic Velickovic, Tanja (Serbia)
08:30h - 09:00h
Liver directed gene therapy for inherited metabolic diseases
Brunetti-Pierri, Nicola (Italy)
08:30h - 09:00h
Looking under the hood of cells: from whole cell organelle reconstructions to single molecule dynamics to atomic reconstructions of macromolecules
Lippincott-Schwartz, Jennifer (United States of America)
11:00h - 12:00h
Initiation of translation by the ribosome
Ramakrishnan, Venki (United Kingdom)
12:00h - 13:00h
A male-essential microRNA is key for avian sex chromosome dosage compensation
Kaessmann, Henrik (Germany)
16:30h - 17:00h
Regulatory RNAs in the brain and neuroendocrine system
Piwecka, Monika (Poland)
16:30h - 17:00h
Engineering polymerases for designed glycans and glycoconjugates
Remaud-Simeon, Magali (France)
16:30h - 17:00h
Development of a highly optimized engineered PETase enzyme for plastic degradation
Parisini, Emilio (Latvia)
16:30h - 17:00h
Symposia
Yellow Room 2+3
1.7.2024
16:30 – 18:30h
Biochemistry of physical activity and health – part B
Chairs: Domenica Scumaci (IT) Juleen R. Zierath (SW)
Mining Skeletal Muscle for Optimal Metabolic Health and Well-Being in Type 2 Diabetes
Zierath, Juleen (Sweden)
16:30h - 17:00h
Symposia
Yellow Room 2+3
1.7.2024
16:30 – 18:30h
Biochemistry of physical activity and health – part B
Chairs: Domenica Scumaci (IT) Juleen R. Zierath (SW)
Compartmentalization in cardiomyocytes modulates kinase activities
Birkedal, Rikke (Estonia)
16:30h - 17:00h
Targeting cancer metabolism by ketogenic diet
Kofler, Barbara (Austria)
17:00h - 17:30h
The interplay of oxygen, diet and microbiota in inflammation and cancer: lessons from fruit flies
Pitsouli, Chrysoula (Cyprus)
17:30h - 18:00h
Symposia
Silver Room
2.7.2024
08:30 – 10:30h
Post-translational modification of membrane proteins
Chairs: Cesare Indiveri (IT) Giuliano Ciarimboli (DE)
Mono-ADP-ribosylation in the control of intracellular membrane traffic
Corda, Daniela (Italy)
08:30h - 09:00h
Symposia
Red Room
2.7.2024
08:30 – 10:30h
Towards sustainable use of natural and renewable resources
Chairs: Salvatore Fusco (IT) Michael O'Donohue (FR)
Synthetic biology for a sustainable recycling and upcycling of PET
Molla, Gianluca (Italy)
08:30h - 09:00h
Metabolite and peptide nanotechnology: implications for materials science and biosensing
Gazit, Ehud (Israel)
09:00h - 09:30h
To degrade or not to degrade: molecular mechanisms of RNA homeostasis
Conti, Elena (Germany)
11:00h - 12:00h
Plenary Lectures
Silver Room
2.7.2024
12:00 – 12:30h
FEBS Letters Lecture
Signaling through the ubiquitin-proteasome system
Schulman, Brenda (Germany)
12:00h - 12:30h
Plenary Lectures
Silver Room
2.7.2024
12:30 – 13:00h
FEBS Open Bio Lecture
Membrane lipids and neural cell signaling: the role of gangliosides
Sonnino, Sandro (Italy)
12:30h - 13:00h
New molecular and cellular insights in cardiovascular diseases
Lavandero, Sergio (Chile)
15:30h - 16:30h
Diurnal cues metabolically regulate Hematopoietic Stem Cell maintenance and function
Chakrabarti, Priyasmita (Israel)
17:00h - 17:30h
The potential of orphan G-protein coupled receptors as novel therapeutic targets
Tunaru, Sorin (Romania)
17:00h - 17:30h
Bioactive lipids supporting the functionality of the epidermal barrier
Nicolaou, Anna (United Kingdom)
17:00h - 17:30h
Precision genetic engineering of hematopoiesis to treat human disease
Naldini, Luigi (Italy)
17:00h - 17:30h
Mechanisms of post-translational modification of microtubules by two distinct families of specific detyrosinases
Anatassis Perrakis (The Netherlands)
08:30h - 09:00h
"Predictions and experiments in structure determination".
Usón, Isabel (Spain)
08:30h - 09:00h
Hydrogen Peroxide Diffusion in the Extracellular Space: Redox Volume Signaling in the Brain
Ledo, Ana (Portugal)
09:00h - 09:30h
Symposia
Blue Room
3.7.2024
08:30 – 10:30h
Young Scientists Session B: Biochemistry for drug repurposing
Chairs: Annamaria Antona (IT) Antonio Ferrer Montiel (ES)
Heterogeneity in tumors: a real-time and single-cell perspective
Snippert, Hugo (Netherlands)
09:00h - 09:30h
Symposia
Blue Room
3.7.2024
08:30 – 10:30h
Young Scientists Session B: Biochemistry for drug repurposing
Chairs: Annamaria Antona (IT) Antonio Ferrer Montiel (ES)
Drug repurposing in neurodegenerative disease: potential and pitfalls
Sultana, Janet (United Kingdom)
08:30h - 09:00h
Symposia
Yellow Room 2+3
3.7.2024
08:30 – 10:30h
The D-side of health: D-amino acids in pathological states
Chairs: Silvia Sacchi (IT) Jean-Pierre Mothet (FR)
Disentangling the many roles of D-serine/NMDA receptor system in the enteric nervous system in health and disease
Mothet, Jean-Pierre (France)
08:30h - 09:00h
Symposia
Yellow Room 2+3
3.7.2024
08:30 – 10:30h
The D-side of health: D-amino acids in pathological states
Chairs: Silvia Sacchi (IT) Jean-Pierre Mothet (FR)
The D-side of neurodevelopmental disorders
Usiello, Alessandro (Italy)
08:30h - 09:00h
The rotary mechanism of ATP synthase; how it is regulated and influences the assembly of the enzyme
Walker, John Ernest (United Kingdom)
11:00h - 12:00h
RNA transport in a large polarized cell
Ephrussi, Anne (Germany)
12:00h - 13:00h
Biomolecular condensates in cellular stress and disease
Alberti, Simon (Germany)
14:00h - 14:30h
Redox-dependent phase separation and cytoplasmic granulation by human single-stranded DNA binding protein 1 (hSSB1) delineate new mechanisms of cellular stress response
Kovacs, Mihaly (Hungary)
14:00h - 14:30h
Regulation of gene expression through transcriptional condensates in C. elegans embryonic development.
Klosin, Adam (Poland)
14:00h - 14:30h
Symposia
Red Room
3.7.2024
14:00 – 16:00h
Impacts of climate change on nutrition and health
Chairs: Stefania Iametti (IT) Célia M. Antunes (PT)
Impacts of climate change on food production and human nutrition
Tuomisto, Hanna (Finland)
14:00h - 14:30h
Symposia
Red Room
3.7.2024
14:00 – 16:00h
Impacts of climate change on nutrition and health
Chairs: Stefania Iametti (IT) Célia M. Antunes (PT)
The biochemistry behind quality and sustainability of plant-based food
Scarafoni, Alessio (Italy)
14:00h - 14:30h
Symposia
Silver Room
3.7.2024
14:00 – 16:00h
From brain molecules to brain functions and diseases
Chairs: Mauro Maccarrone (IT) Mario van der Stelt (NL)
Studying Lipid Metabolism in the Human Brain
van der Stelt, Mario (Netherlands)
14:00h - 14:30h
Symposia
Silver Room
3.7.2024
14:00 – 16:00h
From brain molecules to brain functions and diseases
Chairs: Mauro Maccarrone (IT) Mario van der Stelt (NL)
Deciphering the human blood-brain barrier with in vitro physiological models
Mustafaoglu, Nur (Türkiye)
14:00h - 14:30h
Symposia
Red Room
30.6.2024
08:30 – 10:30h
Cutting edge approaches for sustainable and environmental technology
Chairs: Chiara Schiraldi (IT) Uwe Bornscheuer (DE)
Enzyme Discovery and Engineering for Sustainable Applications in Biocatalysis
Bornscheuer, Uwe (Germany)
08:30h - 09:00h
IDENTIFICATION AND EVOLUTION OF NOVEL CRISPR-CAS SYSTEMS FROM THE HUMAN MICROBIOME
Cereseto, Anna (Italy)
08:30h - 09:00h
Symposia
Blue Room
30.6.2024
17:00 – 19:00h
Bio-based polymers for engineered green materials
Chairs: Loredana Mariniello (IT) Jan Willem Borst (NL)
Biopolymers as a tool for zero-waste materials
Novak, Uroš (Slovenia)
17:30h - 18:00h
Pancreatitis induces transcriptomic and epigenetic reprogramming of epithelial cells to elevate long-lasting cancer predisposition
Carrer, Alessandro (Italy)
17:00h - 17:30h
Symposia
Silver Room
2.7.2024
08:30 – 10:30h
Post-translational modification of membrane proteins
Chairs: Cesare Indiveri (IT) Giuliano Ciarimboli (DE)
Regulation of organic cation transporters
Ciarimboli, Giuliano (Germany)
09:00h - 09:30h
Clinical relevance and potential of functional foods to improve human health
Heiss, Christian (United Kingdom)
17:30h - 18:00h
Exploiting redox-active molecules against mitochondrial diseases
Szabo, Ildiko (Italy)
08:30h - 09:00h
Anticancer compounds isolated from Arctic Marine organisms
Andersen, Jeanette (Norway)
14:30h - 15:00h
Digital twins for complex human diseases: accelerating diagnostics, prognostics and personalized care
Niarakis, Anna (France)
09:00h - 09:30h
Cell Level Simulations and Digital Twins
Valencia, Alfonso (Spain)
08:30h - 09:00h
Revealing the biotechnological potential of marine extremophilic bacteria for the production of novel biosurfactans and other bioactive compounds
de Pascale, Donatella (Italy)
14:00h - 14:30h
Enzyme enhancing strategies: reshaping the treatment landscape of a galactose disorder?
Rubio-Gozalbo, Estela (Netherlands)
09:00h - 09:30h
Symposia
Red Room
2.7.2024
08:30 – 10:30h
Towards sustainable use of natural and renewable resources
Chairs: Salvatore Fusco (IT) Michael O'Donohue (FR)
The development of biorefineries and prospects for the future
O'Donohue, Michael (France)
09:00h - 09:30h
Antivenomics: a translational venomics platform for the preclinical efficacy evaluation of antivenoms
Calvete, Juan J. (Spain)
17:30h - 18:00h
Gene editing for the treatment of inherited liver disorders
Gonzalez-Aseguinolaza, Gloria (Spain)
17:00h - 17:30h
Symposia
Blue Room
30.6.2024
08:30 – 10:30h
Biochemistry of physical activity and health – part A
Chairs: Viberto Stocchi (IT) Paul Greenhaff (UK)
The Impact of Immobilisation and Trauma/Inflammation on Muscle Mass and Insulin Resistance in Humans
Greenhaff, Paul L. (United Kingdom)
09:00h - 09:30h
Special Sessions
Yellow Room 1
1.7.2024
08:30 – 10:30h
New opportunities for researchers – Research infrastructures in imaging, structural biology, human disease modelling and compound screening
Chair: Bahne Stechmann
Welcome & Introduction
Bahne Stechmann, Europe
08:30h - 08:45h
Special Sessions
Yellow Room 1
1.7.2024
08:30 – 10:30h
New opportunities for researchers – Research infrastructures in imaging, structural biology, human disease modelling and compound screening
Chair: Bahne Stechmann
EU-OPENSCREEN - The research infrastructure in chemical biology and early drug discovery
Bahne Stechmann, Europe
08:45h - 09:00h
Special Sessions
Yellow Room 1
1.7.2024
08:30 – 10:30h
New opportunities for researchers – Research infrastructures in imaging, structural biology, human disease modelling and compound screening
Chair: Bahne Stechmann
Instruct-ERIC - Access to latest Structural Biology technologies and training in Europe
John Dolan, Europe
09:00h - 09:15h
Special Sessions
Yellow Room 1
1.7.2024
08:30 – 10:30h
New opportunities for researchers – Research infrastructures in imaging, structural biology, human disease modelling and compound screening
Chair: Bahne Stechmann
Euro-BioImaging - Open access to biological & biomedical imaging technologies and image data services
Daniela Aviles, Europe
09:15h - 09:30h
Special Sessions
Yellow Room 1
1.7.2024
08:30 – 10:30h
New opportunities for researchers – Research infrastructures in imaging, structural biology, human disease modelling and compound screening
Chair: Bahne Stechmann
INFRAFRONTIER – Resources and services for human disease modelling
Michael Raess, Europe
09:30h - 09:45h
Special Sessions
Yellow Room 1
2.7.2024
08:30 – 10:30h
Red Biotechnology
CIB MEETING - Biotechnology: The Contributions of Consorzio Interuniversitario Biotecnologie (CIB)
Chairs: Monica Borgatti (IT) Duccio Cavalieri (IT)
Welcome and CIB overview
Graziano Pesole, Italy
08:30h - 08:45h
Special Sessions
Yellow Room 1
2.7.2024
08:30 – 10:30h
Red Biotechnology
CIB MEETING - Biotechnology: The Contributions of Consorzio Interuniversitario Biotecnologie (CIB)
Chairs: Monica Borgatti (IT) Duccio Cavalieri (IT)
Novel perspectives in cancer biology from the study of the non-repair functions of DNA repair proteins
Gianluca Tell, Italy
08:45h - 09:15h
Special Sessions
Yellow Room 1
2.7.2024
08:30 – 10:30h
Red Biotechnology
CIB MEETING - Biotechnology: The Contributions of Consorzio Interuniversitario Biotecnologie (CIB)
Chairs: Monica Borgatti (IT) Duccio Cavalieri (IT)
Pathogenetic mechanism and personalized medicine: an integrated morphofunctional pathway
Giovanna Cenacchi, Italy
09:15h - 09:45h
Special Sessions
Yellow Room 1
2.7.2024
08:30 – 10:30h
Red Biotechnology
CIB MEETING - Biotechnology: The Contributions of Consorzio Interuniversitario Biotecnologie (CIB)
Chairs: Monica Borgatti (IT) Duccio Cavalieri (IT)
Yeast extracellular vesicles as a tool for anti-inflammatory drug delivery
Duccio Cavalieri, Italy
09:45h - 10:10h
Special Sessions
Yellow Room 1
2.7.2024
08:30 – 10:30h
Red Biotechnology
CIB MEETING - Biotechnology: The Contributions of Consorzio Interuniversitario Biotecnologie (CIB)
Chairs: Monica Borgatti (IT) Duccio Cavalieri (IT)
Molecular engineering of a spheroid-penetrating phage nanovector for targeted photosonodynamic treatment of EGFR-expressing cancer cells
Alberto Danielli - Department of Pharmacy & Biotechnology - University of Bologna, Bologna, Italy.
10:10h - 10:20h
Special Sessions
Yellow Room 1
2.7.2024
17:00 – 19:00h
Green and White Biotechnology
CIB MEETING - Biotechnology: The Contributions of Consorzio Interuniversitario Biotecnologie (CIB)
Chair: Andrea Mazzucato, Daniele Rosellini,Gianluca Molla
Creating Biostimulant Protein Hydrolysates from Olive Supply Chain Wastes
Eleonora Calzoni, Italy
17:00h - 17:25h
Special Sessions
Yellow Room 1
2.7.2024
17:00 – 19:00h
Green and White Biotechnology
CIB MEETING - Biotechnology: The Contributions of Consorzio Interuniversitario Biotecnologie (CIB)
Chair: Andrea Mazzucato, Daniele Rosellini,Gianluca Molla
Metabolic adaptation of ovaries to heat stress at anthesis of durum wheat lines carrying segmental introgressions from the wild grass Thinopyrum ponticum
Ljiljana Kuzmanovic, Italy
17:00h - 17:25h
Special Sessions
Yellow Room 1
2.7.2024
17:00 – 19:00h
Green and White Biotechnology
CIB MEETING - Biotechnology: The Contributions of Consorzio Interuniversitario Biotecnologie (CIB)
Chair: Andrea Mazzucato, Daniele Rosellini,Gianluca Molla
Metabolic flux balance analysis of different reactors performing biological CO2 methanation and biogas upgrading
Stefano Campanaro, Italy
17:35h - 18:00h
Special Sessions
Yellow Room 1
2.7.2024
17:00 – 19:00h
Green and White Biotechnology
CIB MEETING - Biotechnology: The Contributions of Consorzio Interuniversitario Biotecnologie (CIB)
Chair: Andrea Mazzucato, Daniele Rosellini,Gianluca Molla
Chemoenzymatic platforms and cell factories for the transformation of waste materials into bio-based products
Gennaro Agrimi, Italy
18:00h - 18:25h
Special Sessions
Yellow Room 1
2.7.2024
17:00 – 19:00h
Green and White Biotechnology
CIB MEETING - Biotechnology: The Contributions of Consorzio Interuniversitario Biotecnologie (CIB)
Chair: Andrea Mazzucato, Daniele Rosellini,Gianluca Molla
Fungi from extreme environments as a potential tool for ecofriendly agricultural solutions
Laura Bertini-Dipartimento di Scienze Ecologiche e Biologiche. Università degli Studi della Tuscia.
17:25h - 17:35h
Lilia Alberghina
Sysbio/ISBE Centre of Systems Biology Dept Biotecnology and Biosciences University of Milano-Bicocca, Milano, Italy
15:30h - 16:00h
Enhancing learning through student-centered teaching methods
Petchey, Sara (Switzerland)
17:00h - 17:30h
Design a Learning Community to Catalyze Active Learning
Fung, Fun Man (Singapore)
17:30h - 18:00h
Unbiased Screenings Illuminate Regulators of Mitochondria-Endoplasmic Reticulum Contact Sites
Scorrano, Luca (Italy)
08:30h - 09:00h
Modulating amino acid cross-talk between the Tumor and the Host to improve cancer diagnosis and therapy
Erez, Ayelet (Israel)
16:30h - 17:00h
Human Technopole: The power of shared infrastructure and how National Facilities can enhance your research
Marino Zerial (Italy)
14:45h - 15:10h
National Facility for Structural Biology
Paolo Swuec (Italy)
15:10h - 15:30h
AspSnFR: A Genetically-Encoded Biosensor for Real-Time Monitoring of Aspartate in Live Cells
Leippe, Philipp (Austria)
08:30h - 09:00h
Special Sessions
Yellow Room 2+3
30.6.2024
17:00 – 19:00h
Science & Society: Private and public funds in translational research
Chairs: Mauro Magnani (IT) Emmanouil Fragkoulis (GR)
Round Table
Mario Bonaccorso (Italy)
18:30h - 19:00h
The Coalition for Advancing Research Assessment (CoARA): first outcomes of a global initiative
Menico Rizzi, University of Piemonte Orientale (Italy)
13:30h - 13:50h
Evaluation of research proposals at the European Research Council (ERC): The why and what of the recent changes
Alessandra Ferrari, European Research Council Executive Agency
13:50h - 14:10h
Responsible publishing: how your choice of journal impacts science (and your reputation)
Daniela Ruffell, FEBS Press Publisher
14:10h - 14:30h
Symposia
Red Room
30.6.2024
08:30 – 10:30h
Cutting edge approaches for sustainable and environmental technology
Chairs: Chiara Schiraldi (IT) Uwe Bornscheuer (DE)
Construction of engineered Azotobacter vinelandii for increased ammonia production in culture medium
Kang, Yena (Japan)
09:45h - 10:00h
Symposia
Silver Room
30.6.2024
08:30 – 10:30h
Methods and progress in structural biology – part A
Chairs: Martino Bolognesi (IT) Eleonore von Castelmur (SW)
Centromeric protein M18BP1 is a condensin II loading factor
Borsellini, Alessandro (Italy)
09:45h - 10:00h
How to self assemble: oligomeric structures of septin complexes and sub-complexes from Ciona Intestinalis
GARRATT, RICHARD (Brazil)
13:10h - 13:13h
Symposia
Silver Room
30.6.2024
08:30 – 10:30h
Methods and progress in structural biology – part A
Chairs: Martino Bolognesi (IT) Eleonore von Castelmur (SW)
Cryo-EM structure of the SAH-riboswitch involved in the virulence and survival of Pseudomonas aeruginosa
Woźniak, Katarzyna (Poland)
09:30h - 09:45h
Symposia
Silver Room
30.6.2024
08:30 – 10:30h
Methods and progress in structural biology – part A
Chairs: Martino Bolognesi (IT) Eleonore von Castelmur (SW)
Towards an atomic-resolution functional study of the ClpXP machinery in action using cell free and NMR technologies
Astrid, Audibert (France)
10:00h - 10:15h
Tracking transcription-translation coupling in real-time
Duss, Olivier (Germany)
09:30h - 09:45h
An integrative structural biology and molecular biophysics approach towards SOS response characterization: from mechanistic insights to inhibitor screening and design.
Vascon, Filippo (Italy)
09:45h - 10:00h
Structural characterisation and protein tool generation for investigating SLF1 complexes in replication-coupled DNA repair.
Ryder, Emma (United Kingdom)
10:00h - 10:15h
Elucidating the activation mechanism for GBP1 oligomerization – a key player in innate immunity against microbial pathogens
Weismehl, Marius (Germany)
10:15h - 10:30h
Translational proteomic and metabolomic investigations to assess gene therapy/delivery efficacy in rare genetic disease
Menotta, Michele (Italy)
17:30h - 17:45h
The importance of saccharides in GAS1 function
Heras Márquez, Diego (Spain)
18:15h - 18:30h
Multi-omic analyses of hiPSC-derived astrocytes
Tripodi, Farida (Italy)
18:30h - 18:45h
Spatially clustered piRNA genes promote the transcription of piRNAs via condensate formation of the H3K27me3 reader UAD-2
guang, shouhong (China)
17:30h - 17:45h
Identification of cholestasis–induced long non-coding RNAs in liver cells
Maggi, Camilla (Italy)
17:45h - 18:00h
Identification of prognostic biomarkers in hepatocellular carcinoma using a combined quantitative mass spectrometry and in silico analysis approach.
Bocchetti, Marco (Italy)
18:00h - 18:15h
Systematic experimental and computational strategies to identify and functionally characterize lncRNAs and RNA modifications in development and disease
Amaral, Paulo (Brazil)
18:15h - 18:30h
Metal-induced liquid-liquid phase separation of heterochromatin protein 1a
Zakrzewska, Emilia (Poland)
15:30h - 15:45h
Symposia
Red Room
30.6.2024
08:30 – 10:30h
Cutting edge approaches for sustainable and environmental technology
Chairs: Chiara Schiraldi (IT) Uwe Bornscheuer (DE)
Setting up a new Enzymatic Cocktail for the Valorization of Carbohydrates from Lignocellulosic Waste Biomasses
Shaikhibrahim, Ali (Italy)
10:00h - 10:15h
Symposia
Red Room
30.6.2024
08:30 – 10:30h
Cutting edge approaches for sustainable and environmental technology
Chairs: Chiara Schiraldi (IT) Uwe Bornscheuer (DE)
Bioprocessing of agri-food residues into value-added products
Contursi, Patrizia (Italy)
10:00h - 10:15h
Symposia
Red Room
30.6.2024
08:30 – 10:30h
Cutting edge approaches for sustainable and environmental technology
Chairs: Chiara Schiraldi (IT) Uwe Bornscheuer (DE)
Optimization of biotechnological processes, using membranes, to recover different fraction in order to valorise industrial waste
Alfano, Alberto (Italy)
09:00h - 09:15h
Unveiling Research Frontiers: Coherent Anti-Stokes Raman Spectroscopy Insights
G. Argudo, Pablo (Germany)
15:45h - 16:00h
Symposia
Blue Room
30.6.2024
17:00 – 19:00h
Bio-based polymers for engineered green materials
Chairs: Loredana Mariniello (IT) Jan Willem Borst (NL)
Fabrication of electrospun biofiber for biomedical applications
Kars, Gökhan (Türkiye)
18:00h - 18:15h
Symposia
Blue Room
30.6.2024
17:00 – 19:00h
Bio-based polymers for engineered green materials
Chairs: Loredana Mariniello (IT) Jan Willem Borst (NL)
Enzyme-mediated tuning of cellulose surface reactivity for innovative compounding purposes
Alessandrini, Francesca (Italy)
18:15h - 18:30h
Symposia
Blue Room
30.6.2024
17:00 – 19:00h
Bio-based polymers for engineered green materials
Chairs: Loredana Mariniello (IT) Jan Willem Borst (NL)
Exploring SCOBY Bacterial Cellulose Interactions with Graphene Oxide in Kombucha Fermentation
Aulitto, Martina (Italy)
18:30h - 18:45h
Symposia
Red Room
2.7.2024
08:30 – 10:30h
Towards sustainable use of natural and renewable resources
Chairs: Salvatore Fusco (IT) Michael O'Donohue (FR)
Sustainable production of cis,cis-muconic acid production from vanillin by an engineered E. coli strain
Molinari, Filippo (Italy)
09:30h - 09:45h
Symposia
Red Room
2.7.2024
08:30 – 10:30h
Towards sustainable use of natural and renewable resources
Chairs: Salvatore Fusco (IT) Michael O'Donohue (FR)
Sustainable production of carbon nanodots with controlled properties via a green Maillard reaction approach
Nguyen Huu Huong, Duyen (Hungary)
09:45h - 10:00h
Symposia
Red Room
2.7.2024
08:30 – 10:30h
Towards sustainable use of natural and renewable resources
Chairs: Salvatore Fusco (IT) Michael O'Donohue (FR)
Posidonia oceanica egagropili as renewable source for melanin production by Streptomyces nashvillensis
Restaino, Odile Francesca (Italy)
10:00h - 10:15h
Bioactive Preservation: Chitosan/ Poly-γ-glutamic Acid for Cultural Heritage Restoration
Hejazi, Sondos Mohammad Hasan (Italy)
09:30h - 10:00h
The effect of antimicrobial peptides from Antarctic fishes against some viral and bacterial fish pathogens
Buonocore, Francesco (Italy)
15:00h - 15:20h
In vitro bisphenol A impairs testicular energy metabolism and spermatogenesis through nuclear estrogen receptors activation in zebrafish
BATISTA-SILVA, HEMILY (Brazil)
15:20h - 15:40h
Symposia
Blue Room
30.6.2024
08:30 – 10:30h
Biochemistry of physical activity and health – part A
Chairs: Viberto Stocchi (IT) Paul Greenhaff (UK)
Comprehensive multi-omics analysis of serum and fecal samples in a dietary intervention model with pectins for lipid transfer proteins (LTP) food allergy
Macías-Camero, Andrea (Spain)
09:30h - 09:50h
Symposia
Blue Room
30.6.2024
08:30 – 10:30h
Biochemistry of physical activity and health – part A
Chairs: Viberto Stocchi (IT) Paul Greenhaff (UK)
Pharmacological activation of the HIF-1α signaling pathway regulates satellite cells fate during aging through histone lactylation
Cirillo, Federica (Italy)
09:50h - 10:10h
Symposia
Yellow Room 2+3
1.7.2024
16:30 – 18:30h
Biochemistry of physical activity and health – part B
Chairs: Domenica Scumaci (IT) Juleen R. Zierath (SW)
Understanding Ribosomal Protein Distribution and Expression in Neurons and Their Compartments using Single-Cell RNA Sequencing and Single Molecule Microscopy.
Sotelo, José (Uruguay)
17:30h - 17:50h
Symposia
Yellow Room 2+3
1.7.2024
16:30 – 18:30h
Biochemistry of physical activity and health – part B
Chairs: Domenica Scumaci (IT) Juleen R. Zierath (SW)
Inflammatory Activity of Extracellular Vesicles Induced by Different Exercise Regimens
Guescini, Michele (Italy)
17:50h - 18:10h
Inhibition of PUFA mitochondrial metabolism: a novel approach to elevate PUFA levels
Liepins, Edgars (Latvia)
09:30h - 09:45h
A chemical-biological study of bioactive compounds from propolis provides new details on the molecular basis of the anti-inflammatory effects of this multifunctional food
Dal Piaz, Fabrizio (Italy)
09:45h - 10:00h
Trehalose effect in patients with Alzheimer's disease: focus on circulating microRNAs assessed by direct hybridization
Abrego Guandique, Diana Marisol (Italy)
10:00h - 10:15h
A step forward in understanding oleocanthal anti-inflammatory activity by proteomic analysis in microglial cells
Barbalace, Maria Cristina (Italy)
10:15h - 10:30h
Systemic metabolic effects of medium-chain fatty acids supplementation: Insights from murine models
Sternberg, Felix (Austria)
17:30h - 17:50h
Symposia
Red Room
3.7.2024
14:00 – 16:00h
Impacts of climate change on nutrition and health
Chairs: Stefania Iametti (IT) Célia M. Antunes (PT)
Improving salt tolerance in tomato plants through the use of biofertilizers: a biochemical approach
Mekkaoui, Fadoua (Morocco)
15:00h - 15:15h
Symposia
Red Room
3.7.2024
14:00 – 16:00h
Impacts of climate change on nutrition and health
Chairs: Stefania Iametti (IT) Célia M. Antunes (PT)
Biochemical and structural characterization of a newly identified lipase in hazelnut (Corylus avellana)
Fissore, Alex (Italy)
15:15h - 15:30h
Symposia
Red Room
3.7.2024
14:00 – 16:00h
Impacts of climate change on nutrition and health
Chairs: Stefania Iametti (IT) Célia M. Antunes (PT)
Biochemical insights into sustainable plantbased food products: the buckwheat case
Emide, Davide (Italy)
15:30h - 15:45h
Symposia
Red Room
3.7.2024
14:00 – 16:00h
Impacts of climate change on nutrition and health
Chairs: Stefania Iametti (IT) Célia M. Antunes (PT)
The biochemistry for the valorization of agri-food waste and by-products: the case of Okara for sustainable Agri-Tech Applications in Circular Economy.
Periccioli, Lorenzo (Italy)
15:45h - 16:00h
Symposia
Silver Room
2.7.2024
08:30 – 10:30h
Post-translational modification of membrane proteins
Chairs: Cesare Indiveri (IT) Giuliano Ciarimboli (DE)
Post-translational modification of SLC3A2 plays a crucial role in the membrane trafficking of some amino acid transporters belonging to the SLC7 family.
Console, Lara (Italy)
09:00h - 09:20h
Symposia
Silver Room
2.7.2024
08:30 – 10:30h
Post-translational modification of membrane proteins
Chairs: Cesare Indiveri (IT) Giuliano Ciarimboli (DE)
Farnesyl-GFP as a promising fluorescent tag for exosomes labelling
Piccarducci, Rebecca (Italy)
09:50h - 10:10h
Symposia
Silver Room
2.7.2024
08:30 – 10:30h
Post-translational modification of membrane proteins
Chairs: Cesare Indiveri (IT) Giuliano Ciarimboli (DE)
Structural insights into vesicular monoamine transport and neurological drug interactions
Li, Weikai (United States of America)
10:10h - 10:30h
Sweet Golgi - the role of vesicular tethers and SNAREs in Golgi glycosylation
Lupashin, Vladimir (United States of America)
09:50h - 10:10h
Impact of lysosomal nutrient sensing on metabolic dysregulation
Bhardwaj, Meenakshi (United Kingdom)
10:10h - 10:30h
Structure-function studies of human MICAL1, the multidomain flavoenzyme participating in actin cytoskeleton dynamics
Vanoni, Maria Antonietta (Italy)
09:30h - 09:45h
NADPH Regeneration via Renewable Hydrogen: Exploiting Oxygen-Resistant [FeFe]-Hydrogenase and BMR Reductase in a Non-Physiological Cascade
Valetti, Francesca (Italy)
09:45h - 10:00h
Biochemical portrait of the inner-membrane associated cytochrome CbcA: insights into its role in extracellular electron transfer
Antunes, Jorge M. A. (Portugal)
10:00h - 10:15h
The antioxidant function of coenzyme A: a renaissance of a key metabolic cofactor
Filonenko, Valeriy (Ukraine)
10:15h - 10:30h
Novel GH109 enzymes for bioconversion of group A red blood cells to the universal donor group O
Iacono, Roberta (Italy)
17:30h - 17:45h
Divergent genetic evolution employs the same molecular mechanisms
Frøhlich, Christopher (Norway)
17:45h - 18:00h
Enhancing the thermal stability and activity of the artificial self-sufficient P450SPα-SOX by switching the domains linker
Giuriato, Daniele (Italy)
18:00h - 18:15h
Development of an enzymatic treatment for valorizing (recycling and upcycling) PET-textile waste
Zangelmi, Erika (Italy)
18:15h - 18:30h
Drug and genetic material co-loaded liposomes for repairing chondrocytes in Osteoarthritic conditions
Ranamalla, Saketh Reddy (Romania)
09:30h - 09:50h
Red blood cells-derived extracellular vesicles for the loading and delivery of RNA molecules
Biagiotti, Sara (Italy)
09:50h - 10:10h
Mycobacterium tuberculosis methionine aminopeptidase a new target for the development of novel antitubercular compounds.
Cocorullo, Mario (Italy)
10:10h - 10:30h
Symposia
Yellow Room 2+3
3.7.2024
08:30 – 10:30h
The D-side of health: D-amino acids in pathological states
Chairs: Silvia Sacchi (IT) Jean-Pierre Mothet (FR)
Biological effects of the loss of homochirality in a multicellular organism
Banreti, Agnes (France)
09:30h - 09:50h
Symposia
Yellow Room 2+3
3.7.2024
08:30 – 10:30h
The D-side of health: D-amino acids in pathological states
Chairs: Silvia Sacchi (IT) Jean-Pierre Mothet (FR)
Synthesis and Biological Evaluation of Olanzapine-based PROTACs Targeting Human D-Aspartate Oxidase (hDASPO)
Citarella, Andrea (Italy)
09:50h - 10:10h
Symposia
Yellow Room 2+3
3.7.2024
08:30 – 10:30h
The D-side of health: D-amino acids in pathological states
Chairs: Silvia Sacchi (IT) Jean-Pierre Mothet (FR)
New insights in the function and regulation of the phosphorylated pathway for serine biosynthesis in the human brain
Campanini, Barbara (Italy)
10:10h - 10:30h
Viral and non-viral vectors for the delivery of genome editing tools to mammalian cells
Dirvelyte, Eimina (Lithuania)
09:45h - 10:00h
Rad51-based editing of mitochondrial DNA via CRISPR approach
Sukhorukov, Vasily (Russia)
10:00h - 10:15h
Fine-tuning site-directed RNA editing: controlled gRNA synthesis with T7 RNA polymerase
Conticello, Silvestro (Italy)
18:00h - 18:15h
Moonlighting role for dUTPase: establishing a viable mammalian cell line with high uracil-DNA levels
Nagy, Nikolett (Hungary)
18:15h - 18:30h
Exploiting the role of miR-155 in triple negative breast cancer via CRISPR/Cas9 based genome editing
Ferreira, Débora (Portugal)
18:30h - 18:45h
Hypoxia increases methylated histones to prevent histone clipping
PARK, Hyunsung (South Korea)
18:00h - 18:15h
PARP1 regulates 3D structure and function of super-enhancers and hormone-control regions
Ferrari, Roberto (Italy)
18:15h - 18:30h
HIF1A-EP300-BRG1 functional crosstalk on the chromatin defines transcription of ABC transporters in paclitaxel resistant breast and lung cancers
Gronkowska, Karolina (Poland)
18:30h - 18:45h
Simultaneous targeting of LSD1 and PRMT5 through chimeric inhibitors as a novel therapeutic approach against leukemia
Fiorentino, Francesco (Italy)
18:45h - 19:00h
Deciphering the Role of Cytokine-Induced Glutamate Dynamics in Breast Cancer Brain Metastasis
Di Russo, Sara (Italy)
17:30h - 17:45h
Unraveling metabolic vulnerabilities to counteract sorafenib resistance in hepatocellular carcinoma
Mitro, Nico (Italy)
18:15h - 18:30h
Spatial Flux Balance Analysis reveals spatially resolved metabolic heterogeneity in renal cancer
Damiani, Chiara (Italy)
09:30h - 09:45h
Learning and applying general principles of cancer cell drug sensitivity
Carli, Francesco (Italy)
09:45h - 10:00h
An adaptable in silico model of the arachidonic acid cascade
Horne, Grace (United Kingdom)
10:00h - 10:15h
Integrative discovery of SARS-CoV-2 Mpro inhibitors through virtual screening and in vitro validation
Gevorgyan, Smbat (Armenia)
10:15h - 10:30h
Emerging role of the Succinate/SUCNR1 axis in microglial metabolism: from physiology to pathology
Repollés-de-Dalmau, Maria (Spain)
18:00h - 18:20h
Dissecting the sequence and structure determinants of gpcr - gprotein selectivity via structural bioinformatics and machine learning
Matic, Marin (Italy)
18:20h - 18:40h
Molecular insights into G-protein specificity and biased agonism at the β2-adrenergic receptor
Casiraghi, Marina (Italy)
18:40h - 19:00h
Symposia
Silver Room
3.7.2024
14:00 – 16:00h
From brain molecules to brain functions and diseases
Chairs: Mauro Maccarrone (IT) Mario van der Stelt (NL)
Aβ1-6A2V(D): a bio-inspired peptide as potential multitarget treatment for tauopathies
Mosconi, Michele (Italy)
15:00h - 15:20h
Symposia
Silver Room
3.7.2024
14:00 – 16:00h
From brain molecules to brain functions and diseases
Chairs: Mauro Maccarrone (IT) Mario van der Stelt (NL)
Optimizing performance characteristics of antibodies for single-molecule quantitative bioimaging
Breiter, Jonathan Claas (United Kingdom)
15:20h - 15:40h
Symposia
Silver Room
3.7.2024
14:00 – 16:00h
From brain molecules to brain functions and diseases
Chairs: Mauro Maccarrone (IT) Mario van der Stelt (NL)
Molecular basis of coupling Ca2+-sensing to fast membrane fusion by Synaptotagmin-1 in neurotransmitter release
Jaczynska, Klaudia (United States of America)
15:40h - 16:00h
Aggregate-binding aptamers for Parkinson´s disease diagnostics
Nowinska, Magdalena (United Kingdom)
09:30h - 09:50h
Development of Paper-Based Origami Biosensor Platform for Microorganism Monitoring
Sözmen, Alper Baran (Türkiye)
09:50h - 10:10h
Exploring the potential of yeast cells as biosensors for environmental monitoring
Guaragnella, Nicoletta (Italy)
10:10h - 10:30h
Symposia
Blue Room
3.7.2024
08:30 – 10:30h
Young Scientists Session B: Biochemistry for drug repurposing
Chairs: Annamaria Antona (IT) Antonio Ferrer Montiel (ES)
Synthetic Antimalarial Peptides to Combat Drug Resistance in Malaria
Kiper, Edo (Israel)
09:30h - 09:45h
Symposia
Blue Room
3.7.2024
08:30 – 10:30h
Young Scientists Session B: Biochemistry for drug repurposing
Chairs: Annamaria Antona (IT) Antonio Ferrer Montiel (ES)
The antipsychotic drug penfluridol displays cytotoxicity in breast cancer cells by inducing mitochondrial damage and activating the endoplasmic reticulum stress response
Antona, Annamaria (Italy)
10:00h - 10:15h
Symposia
Blue Room
3.7.2024
08:30 – 10:30h
Young Scientists Session B: Biochemistry for drug repurposing
Chairs: Annamaria Antona (IT) Antonio Ferrer Montiel (ES)
High-density lipoprotein engineering for treatment of age-related macular degeneration
Murakami, Tatsuya (Japan)
09:45h - 10:00h
The unique allosteric regulation of crocodilian hemoglobin revealed by Cryo-EM
Takahashi, Katsuya (Japan)
13:13h - 13:16h
Damage recognition process in DNA repair pathway: cryo-EM-based analysis of the UvrA-UvrB complex in Mycobacterium tuberculosis
Genta, Marianna (Italy)
13:16h - 13:19h
Structural description of the multivalent interaction of the post-synaptic scaffold protein GKAP and dynein motor molecule
Nagy-Kanta, Eszter (Hungary)
13:19h - 13:22h
Investigation of Maternal Diabetes Effects on Metabolomic Profile of Umbilical Cord Blood Plasma by IVDr NMR Spectroscopy
Uslu, Gizem (Türkiye)
13:22h - 13:25h
Exploring potential biomarkers for the correlation between inflammation and Age-Related Hearing Loss (ARHL)
García Montoya, Carmen (Spain)
13:25h - 13:28h
PETzyme: Towards a novel enzymatic immobilization strategy for biorecycling of plastic waste
López Teijeiro, Adrián (Spain)
13:10h - 13:13h
Exploring the copper-detoxification mechanisms of wild-type Pseudomonas strains as a potential tool for metal-polluted environments remediation
Havryliuk, Olesia (Ukraine)
13:13h - 13:16h
Use of anthocyanin enriched fraction of C. citrinus for the functionalization of PVA-based bioplastic
Patané, Giuseppe Tancredi (Italy)
13:16h - 13:19h
Mechanical, barrier and thermal properties of hydrocolloid-based bioplastics from amylose and argan proteins prepared in the presence of transglutaminase and magnetic nanoparticles
Famiglietti, Michela (Italy)
13:19h - 13:22h
Enhancement of H2 production by Chlorella vulgaris using potato peel waste
Manoyan, Jemma (Armenia)
13:22h - 13:25h
Structural and biochemical studies of the hepatitis C virus envelope proteins to promote germline-targeting vaccine design
Yechezkel, Itai G (Israel)
13:10h - 13:13h
Development of new humanized monoclonal antibodies for the treatment of fungal infections
Vanzolini, Tania (Italy)
13:13h - 13:16h
Phage display-derived monoclonal antibodies against the staphylococcal collagen adhesin CNA
Restivo, Elisa (Italy)
13:16h - 13:19h
Pleiotrophin enhances mTORC1 activity and protein synthesis in endothelial cells through crosstalk of multiple receptors
Mourkogianni, Eleni (Greece)
13:19h - 13:22h
Probing the nucleobase selectivity of RNA polymerases with C-nucleoside antibiotics
Mäkinen, Janne J (Finland)
13:22h - 13:25h
Sialidase Neu3: a Novel Cardioprotective Target against Ischemia and Reperfusion Injury
Piccoli, Marco (Italy)
13:10h - 13:13h
Inhibiting the Escape: Unveiling the Potential of Type I PRMT Inhibitors in Targeting Lysosomal Exocytosis for Improved Cancer Therapy
Sergi, Baris (Türkiye)
13:16h - 13:19h
Alterations in the expression and subcellular localization of the SWI/SNF chromatin remodeling complexes subunits and their potential clinical significance in clear cell renal cell carcinoma
Wilga, Magdalena (Poland)
13:19h - 13:22h
MUTANT P53 (MUTP53)-DRIVEN HMGA1 SECRETION PROMOTES PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) PROLIFERATION AND CHEMORESISTANCE
Fiore, Alessandra (Italy)
13:22h - 13:25h
Serine-glycine metabolism drives VEGFR2 modulated tumorigenesis
Ventura, Anna (Italy)
13:25h - 13:28h
Calcium transport by sarcoplasmic reticulum Ca2+-ATPase: stimulatory and inhibitory effects investigated on a solid supported membrane
Tadini-Buoninsegni, Francesco (Italy)
13:10h - 13:13h
Aquaporin-3 and aquaporin-5 modulate cell biomechanical properties and influence cell migration
Pimpão, Catarina (Portugal)
13:13h - 13:16h
Sec24D-positive ER exit sites sort raft-preferring proteins for rapid ER export.
Castello-Serrano, Ivan (Italy)
13:16h - 13:19h
Regulation of human Akt1 by phosphatidylinositol (3,4,5)-trisphosphate lipid species
Bahra, Obada (Germany)
13:19h - 13:22h
Nonmuscle Myosin II participates in controlling the fission of cellular organelles
Jana, Siddhartha (India)
13:22h - 13:25h
T-cell-restricted intracellular antigen-1 directs cellular senescence by regulating mitochondrial dynamics
Lee, Eun Kyung (South Korea)
13:25h - 13:28h
Integrative multi-omics approach in subjects affected by Glycogen storage disease type Ia
Pirozzi , Francesca (Italy)
13:10h - 13:13h
Effect of nutrient stress on protein stability in the bioplastic producer Cupriavidus necator – monitoring conformation at proteome level using thermal proteomics
McKeever, Kate (Ireland)
13:13h - 13:16h
The hyperactivity of Estrogen Receptor fusion proteins in breast cancer
Gherghelas, Ana-Maria (United Kingdom)
13:16h - 13:19h
Chemotactic interactions drive migration of membraneless active droplets
Bevilacqua, Alessandro (Japan)
13:19h - 13:22h
Exploring the redox properties of flavocytochrome c from Shewanella sp. DSM9451 – Comparison between pathogenic and non-pathogenic Shewanella species
Firmino, Maria O. (Portugal)
13:22h - 13:25h
Exploring the antimicrobial potential of natural compounds inducing oxidative stress on Rhodococcus fascians
Llano Verdeja, Jesús (Spain)
13:25h - 13:28h
Opuntia Ficus Indica fruit ameliorates glucose dysmetabolism in a murine model of metabolic syndrome: a comparative study with chromium picolinate.
Massaro, Alessandro (Italy)
13:10h - 13:13h
The study of the interaction between ampelopsin, myricetin, and their sulfate conjugates and multispecific organic anion-transporting polypeptides (OATP1B1, OATP2B1)
Kaci, Hana (Hungary)
13:13h - 13:16h
In vitro effects of resveratrol supplementation of plasma from patients affected by Alzheimer’s Disease on cultured human endothelial cells
Membrino, Valentina (Italy)
13:16h - 13:19h
Biochemical aspects of food sustainability: molecular basis of bread improvement through enrichment with sprouted legumes flour
Borgonovi, Sara Margherita (Italy)
13:19h - 13:22h
Cadmium-induced growth and physiological disruptions in wheat
ZAARI JABRI, Nada (Morocco)
13:22h - 13:25h
Substrate recognition mechanisms and cleavage modes by human separase
Botto, Margherita (Switzerland)
13:25h - 13:28h
Semaphorin3A switches cancer associated fibroblasts towards an anti-tumor phenotype in pancreatic ductal adenocarcinoma
Cojocaru, Carina Florina (Italy)
13:10h - 13:13h
Systematic identification of druggable PKA substrates involved in colon cancer progression
Kugler, Valentina (Austria)
13:13h - 13:16h
Mechanisms regulating lipid storage in breast cancer cells
Lanzetti, Letizia (Italy)
13:16h - 13:19h
Hexosamine biosynthetic pathway inhibition cooperates with gemcitabine inducing in vitro and in vivo pancreatic cancer regression by enhancing DNA damage
Chiaradonna, Ferdinando (Italy)
13:19h - 13:22h
A Mass Spectrometry Imaging-based multiomics approach to map the tumour-immune landscape of clear cell Renal Cell Carcinoma and gain insights into resistance to immunotherapy
Bindi, Greta (Italy)
13:25h - 13:28h
Type 2 Transglutaminase inhibition deregulates MIR210HG lncRNA expression impacting hypoxia-related genes in triple-negative breast cancer cell line
Ancona, Pietro (Italy)
13:10h - 13:13h
RNA regulates transcription via hybrid-triplex formation
Cencini, Aura (Italy)
13:13h - 13:16h
Repositioning a novel precursor of the HIV-1 protease inhibitor Darunavir: antiproliferative effect, autophagy activation and proteasome inhibition by RDD-142 in hepatocarcinoma cell line HepG2
Armentano, Maria Francesca (Italy)
13:16h - 13:19h
Structural characterization of thioredoxin reductase from Cryptosporidium parvum and its interaction with auranofin
Gabriele, Federica (Italy)
13:19h - 13:22h
Exploring interaction sites of arrestin and Y1R/Y2R utilizing genetic code expansion
Mohr, Alexander (Germany)
13:22h - 13:25h
VDAC1-based gene therapy recovers mitochondrial respiration by enhancing the complex I-sirtuins axis in a mice model of ALS
Magrì, Andrea (Italy)
13:25h - 13:28h
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension
Santamans Recchini, Ayelén Melina (Spain)
13:10h - 13:13h
Investigation of the role of Wnt/β-catenin signaling in development of Alzheimer's disease in a zebrafish model of amyloid-β toxicity
NAZLI, Makbule Dilek (Türkiye)
13:13h - 13:16h
Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions
Antón, Rosa (Spain)
13:16h - 13:19h
Analysis of the molecular basis of senataxin-associated amyotrophic lateral sclerosis
Giannini, Marta (France)
13:19h - 13:22h
The Cancer Genome Explorer (TCGEx): A powerful visual interface for sophisticated analyses of high throughput cancer data
Ekiz, H. Atakan (Türkiye)
13:22h - 13:25h
Dissecting the role of glutamine metabolism in anaplerosis and redox homeostasis in K-ras-transformed mouse fibroblasts
Sacco, Elena (Italy)
13:25h - 13:28h
Evolution of marine contagious cancers in cockles characterized by genomic instability.
Bruzos, Alicia L (France)
13:10h - 13:13h
Cubosome drug nanocarriers loaded with algae extract for Photodynamic Therapy in pancreatic cancer treatment
Krautforst, Karolina (Poland)
13:13h - 13:16h
A multi-omic study of nicotine catabolism in Paenarthrobacter nicotinovorans
El-Sabeh, Amada (Romania)
13:16h - 13:19h
Discovery and Engineering of Improved Biocatalysts for the Synthesis of Biodegradable Plastic Copolymers (BioCat4BioPol)
Guglielmi, Giulia (Italy)
13:19h - 13:22h
Unlocking the potential of cohesin-dockerin interactions: mini-cellulosomal complexes from Clostridium thermocellum and their impact on enzymatic biomass degradation
Waghmare, Snehal Dattatray (India)
13:22h - 13:25h
Bifidobacterium animalis subsp. lactis HN019 live probiotics and postbiotics: production strategies and bioactivity evaluation for potential therapeutic properties
D'ambrosio, Sergio (Italy)
13:25h - 13:28h
A multi-omic analysis reveals gender-specific D-serine signatures in Alzheimer's disease
Maffioli, Elisa (Italy)
13:10h - 13:13h
Investigating the impact of the pathological human phosphoserine phosphatase N133S variant on serine synthesis
Motta, Zoraide (Italy)
13:13h - 13:16h
Human serine racemase: structural flexibility and interaction with protein partners
Faggiano, Serena (Italy)
13:16h - 13:19h
Blood-brain barrier permeability increases with the differentiation of glioblastoma cells
Salaroglio, Iris Chiara (Italy)
13:19h - 13:22h
Boosting NAD in senescent microglia, a useful strategy to counteract neurodegeneration?
Astigiano, Cecilia (Italy)
13:22h - 13:25h
Bisphenol A, an endocrine disruptor that links obesity and neurodegeneration, a zebrafish study
Beler, Merih (Türkiye)
13:25h - 13:28h
Nutraceutical supplementation on behavioral and biochemical alterations in fibromyalgia
Marino, Ylenia (Italy)
18:20h - 18:40h
Antioxidant, anti-inflammatory, and antibacterial activities of pomegranate peel and tomato skin extracts in Human Primary Gingival Epithelial Cells.
Silla, Alessia (Italy)
18:40h - 19:00h
Symposia
Blue Room
30.6.2024
17:00 – 19:00h
Bio-based polymers for engineered green materials
Chairs: Loredana Mariniello (IT) Jan Willem Borst (NL)
From agrifood waste towards novel bio-based materials
Digiovanni, Stefania (Italy)
18:45h - 19:00h
Symposia
Blue Room
30.6.2024
08:30 – 10:30h
Biochemistry of physical activity and health – part A
Chairs: Viberto Stocchi (IT) Paul Greenhaff (UK)
INVESTIGATION OF SERUM IRISIN,ADROPIN AND PREPTIN VALUES IN OBESE AND NON-OBESE INDIVIDUALS
Katar, Muzaffer (Türkiye)
09:50h - 10:10h
Voltage Dependent Anion-selective Channel (VDAC), the gatekeeper of mitochondria, as a signaling hub for diseases
De Pinto, Vito
08:30h - 08:50h
CRISPR CGBE1-based editing on CD34+ stem cells to grow Bombay blood group compatible red blood cells
Kurghinyan, Mher (Armenia)
09:00h - 09:15h
Applying autophagy as a treatment for Huntington's disease
Kurghinyan , Mane (Armenia)
13:10h - 13:13h
Tissue metabolite composition driving metastatic organotropism in prostate cancer: the role of asparagine
Pranzini, Erica (Italy)
13:19h - 13:22h
Special Sessions
Yellow Room 1
2.7.2024
08:30 – 10:30h
Red Biotechnology
CIB MEETING - Biotechnology: The Contributions of Consorzio Interuniversitario Biotecnologie (CIB)
Chairs: Monica Borgatti (IT) Duccio Cavalieri (IT)
A comparison of the antitumor efficacy of novel multi- specific tribodies with combinations of approved immunomodulatory antibodies.
Margherita Passariello – Dipartimento di Medicina Molecolare e Biotecnologie Mediche. Università degli Studi di Napoli Federico II, Napoli (Italia).
10:20h - 10:30h
Special Sessions
Yellow Room 1
2.7.2024
17:00 – 19:00h
Green and White Biotechnology
CIB MEETING - Biotechnology: The Contributions of Consorzio Interuniversitario Biotecnologie (CIB)
Chair: Andrea Mazzucato, Daniele Rosellini,Gianluca Molla
The green recovery of insect-derived chitin and its use for different biotechnological applications.
Daniele Bruno- Dipartimento di Biotecnologie e Scienze della vita. Università degli Studi Insubria, Varese
18:25h - 18:35h
Patrick England
Institut Pasteur, Paris, France
15:30h - 15:45h
Francesca Cutruzzolà
Sapienza University, Rome, Italy
15:45h - 16:00h
Ancient proteins: current challenges in identification and characterization
Birolo, Leila (Italy)
10:00h - 10:30h
Ferrari, Alessandra
European Research Council Executive Agency, Brussels, Belgium. With the participation of ERC grantees Elena Conti and Brenda Schulman
15:00h - 15:30h
Industry Sessions
Yellow Room 1
1.7.2024
15:00 – 15:30h
Thermo Fisher Symposium
Enhancing Resolution and Throughput in Structural Biology: The role of Cryo-EM
Deniz Ugurlar
15:00h - 15:30h
Special Sessions
Yellow Room 2+3
30.6.2024
17:00 – 19:00h
Science & Society: Private and public funds in translational research
Chairs: Mauro Magnani (IT) Emmanouil Fragkoulis (GR)
EIF’s key role at fostering investments in Technology Transfer in the Life Science sector
Immaculada Valle (Luxembourg)
18:00h - 18:30h
Protein misfolding and aggregation: role in aging, neurodegeneration, non-neuropathic diseases and cancer
Chiti, Fabrizio (Italy)
16:30h - 17:00h
Symposia
Silver Room
30.6.2024
08:30 – 10:30h
Methods and progress in structural biology – part A
Chairs: Martino Bolognesi (IT) Eleonore von Castelmur (SW)
Structural Enzymology on EMBL beamlines at PETRA III
Schneider, Thomas Richard (Germany)
10:15h - 10:30h
Osmoadaptation in yeast cells with mitochondrial dysfunction:gaining insight into stress signaling networks
Di Noia, Maria Antonietta (Italy)
13:25h - 13:28h
Symposia
Blue Room
3.7.2024
08:30 – 10:30h
Young Scientists Session B: Biochemistry for drug repurposing
Chairs: Annamaria Antona (IT) Antonio Ferrer Montiel (ES)
Tacrolimus, a topical calcineurin inhibitor, could be used as a candidate compound for chondrosarcoma treatment.
Tuncal, Akıle (Cyprus)
10:15h - 10:30h
Special Sessions
Yellow Room 1
3.7.2024
08:30 – 10:30h
Immunotherapy: treatment and prevention of infectious and tumor diseases (Immuno-HUB)
Chairs: Caterina Temporini (IT) Roberta Bernardini (IT)
Welcome & Introduction
Marco Terreni, Principal Investigator, University of Pavia
08:30h - 08:45h
Special Sessions
Yellow Room 1
3.7.2024
08:30 – 10:30h
Immunotherapy: treatment and prevention of infectious and tumor diseases (Immuno-HUB)
Chairs: Caterina Temporini (IT) Roberta Bernardini (IT)
Objective 1 - Design and development of glycoconjugate vaccines against tuberculosis
Sara Tengattini, University of Pavia, Italy
08:45h - 09:00h
Special Sessions
Yellow Room 1
3.7.2024
08:30 – 10:30h
Immunotherapy: treatment and prevention of infectious and tumor diseases (Immuno-HUB)
Chairs: Caterina Temporini (IT) Roberta Bernardini (IT)
Objective 2 - Recombinant production and characterization of SARS-CoV-2 antigens and their human receptors
Federico Forneris, University of Pavia, Italy
09:00h - 09:15h
Special Sessions
Yellow Room 1
3.7.2024
08:30 – 10:30h
Immunotherapy: treatment and prevention of infectious and tumor diseases (Immuno-HUB)
Chairs: Caterina Temporini (IT) Roberta Bernardini (IT)
Objective 3 - Development and Characterization of SARS-CoV-2 specific human monoclonal antibodies for clinical use
Gaia Donetti, IRCSS Policlinico San Matteo Pavia, Italy
09:15h - 09:30h
Special Sessions
Yellow Room 1
3.7.2024
08:30 – 10:30h
Immunotherapy: treatment and prevention of infectious and tumor diseases (Immuno-HUB)
Chairs: Caterina Temporini (IT) Roberta Bernardini (IT)
Objective 4 - The nicotinamide phosphoribosyltransferase (NAMPT) as a novel therapeutic target for the treatment of glioblastoma multiforme
Greta Cascetta, University of Pavia, Italy
09:30h - 09:45h
Special Sessions
Yellow Room 1
3.7.2024
08:30 – 10:30h
Immunotherapy: treatment and prevention of infectious and tumor diseases (Immuno-HUB)
Chairs: Caterina Temporini (IT) Roberta Bernardini (IT)
Objective 5 - Data Driven exploration of GPCRs as therapeutic targets in cancer
Francesco Raimondi, University of Pavia, Italy
09:45h - 10:00h
Special Sessions
Yellow Room 1
3.7.2024
08:30 – 10:30h
Immunotherapy: treatment and prevention of infectious and tumor diseases (Immuno-HUB)
Chairs: Caterina Temporini (IT) Roberta Bernardini (IT)
Objective 6 - Novel frontiers in immunotherapy for Renal cell carcinoma: from bench to bedside
Marco Stellato, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy
10:00h - 10:15h
NMR perspective of cellular processes
Roberta Pierattelli, Italy
16:30h - 17:00h
Nanobodies for structural biology and beyond
Els Pardon, Belgium
17:00h - 17:30h
Visualization of protein biogenesis at organelle membranes and under persistent stress
Friedrich G. Förster, The Netherlands
17:30h - 18:00h
Calcium influence on the human Nedd4-2 enzyme and its ability to form a complex with 14-3-3η
Maša Janosev, Czech Republic
18:00h - 18:15h
Modulating the 'in vitro' oligomerization of SMAD4
Miriam Condeminas, Spain
18:15h - 18:30h
Symposia
Red Room
2.7.2024
08:30 – 10:30h
Towards sustainable use of natural and renewable resources
Chairs: Salvatore Fusco (IT) Michael O'Donohue (FR)
Towards sustainable processes: use of agro-food waste biomasses to produce recombinant proteins
Mangiagalli, Marco (Italy)
10:15h - 10:30h
Industry Sessions
Yellow Room 1
30.6.2024
14:30 – 15:00h
REFEYN Symposium
Understanding biomolecular behaviour using mass photometry
Perla Vega Dominguez
14:30h - 15:00h
Industry Sessions
Yellow Room 1
1.7.2024
14:00 – 14:30h
Agilent Symposium
Agilent Workflow for Cancer Research and Immunotherapy
Emma Nora Di Capua, Phd, MBA Channel Partner Manager EMEA CLSD Agilent Technologies & Claudia Scaccabarozzi, Market Specialist Molecular & Biological Research DGG Agilent Technologies
14:00h - 14:30h